In vitro activity of the quinolone WCK 771 against recent U.S. hospital and community-acquired Staphylococcus aureus pathogens with various resistance types.

نویسندگان

  • Sachin S Bhagwat
  • Pamela McGhee
  • Klaudia Kosowska-Shick
  • Mahesh V Patel
  • Peter C Appelbaum
چکیده

WCK 771 demonstrated MIC(50) and MIC(90)s of 0.03 and 1 microg/ml, respectively, against 297 recent U.S. community-acquired and hospital strains of Staphylococcus aureus, irrespective of quinolone or glycopeptide resistance. Against quinolone-resistant strains, MIC(90)s of WCK 771 and moxifloxacin were 1 and 16 microg/ml, respectively.

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Antistaphylococcal activity of WCK 771, a tricyclic fluoroquinolone, in animal infection models.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 53 2  شماره 

صفحات  -

تاریخ انتشار 2009